Thymidine kinase activities in mononuclear leukocytes and serum from breast cancer patients
نویسندگان
چکیده
منابع مشابه
Elevated levels of thymidine kinase 1 peptide in serum from patients with breast cancer
OBJECTIVES Thymidine kinase (TK) has an important role in DNA synthesis and is thus related to cell proliferation and turn-over. Traditionally, TK has been measured by enzymatic activity or radioimmunoassays. These assays are difficult to adapt to random access instruments. The aim of this study was to evaluate a new immunological sandwich assay for detection of TK peptides in serum from breast...
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Breast cancer is a complex genetic disease that has an average annual incidence of two million people and the second leading cause of death among women all over the world. Micro-RNAs are consistently reported to regulate gene expression in all cancers. The present study, the correlation between the expression of hsa-miR-490-5p and nuclear factor of activated T-cells 5 (NFAT5) in breast cancer w...
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BACKGROUND Thymidine kinase (TK) plays an essential role in the processing of thymidine within the cell and therefore it is an important marker of proliferation, particularly in tumor cells. The aim of our study was to determine the diagnostic, prognostic and predictive importance of TK measurement in cancer. PATIENTS AND METHODS TK was measured using radioreceptor analysis (RRA) with Immunot...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1988
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1988.141